An overview of fibroblast growth factor 23 and its role in kidney function

Fibroblast growth factor 23 (FGF23) is a hormone that plays critical role in regulating mineral homeostasis the body. Specifically, FGF23 acts on kidneys to decrease reabsorption of phosphate from blood and into urine. This process helps reduce serum levels maintain balance alongside other hormones such as PTH. The primary responsibility regulate It does this by acting kidney cells allows body excrete excess normal blood. In addition levels, also metabolism vitamin D. can increase D an inactive form, reducing amount active reduction leads decreased intestinal absorption dietary calcium phosphate. Abnormal have been associated with several health concerns, particularly patients chronic disease. High linked development bone loss, vascular calcification, cardiovascular Conversely, low increased risk mortality disease